Packaging and Zoonosis

coli, Klebsiella spp., Salmonella spp., Shigella spp., Campylobacter spp.; gram (+) m / o - Staph. Method of production of drugs: Table., Coated, of 0,1 g here a bactericidal action, active mainly against aerobic gram (-) flora of the family Enterobacteriaceae, with up to amikacin susceptible strains of many bacteria resistant to other aminoglycosides. faecalis and its varieties (including Str. The main adverse reactions are nephrotoxicity and ototoksychnist, most often in children, the elderly and the source of impaired renal function and hearing. Contraindications backset the use of drugs: hypersensitivity to aminoglycoside groups and their derivatives; severe renal insufficiency, the auditory nerve neuritis, pregnancy, lactation. Given the resistance of pneumococcus, aminoglycosides (including gentamicin) can not be used for outpatient treatment of P. Side effects and complications in the use of drugs: nephrotoxicity (increase or decrease significantly the frequency of backset or the urine, increased thirst, loss of appetite, nausea, vomiting), proteinuria, cylindruria, creatinine increase, residual nitrogen, neurotoxicity (muscle twitching, zaterplist, epileptic seizures, ringing in the ears), ototoksychnist (loss or hearing loss, podzenkuvannya, buzz or feeling of fullness in the ears), vestibular toxicity (disturbance of coordination, tremors, nausea, vomiting), rarely - or hypersensitivity of neuromuscular blocking ( difficulties breathing, heaviness and weakness), AR (skin rash, itching, fever, swelling edema), a change of peripheral blood (anemia, leukopenia, granulocytopenia, thrombocytopenia), increase of transaminases levels. (Including indolpozytyvni indolnehatyvni and strains), E. Apply with various infections, including nosocomial caused by aerobic gram (-) flora, the suspected etiology of mixed - coupled with?-actams antyanaerobnymy and drugs (linkozamidy). faecium, Str. Contraindications to the use of drugs: hypersensitivity to the drug, fungal disease, liver backset kidney disease, pregnancy, lactation, infancy to 8 years. Anaerobes are resistant. Indications for use drugs: bacterial pneumonia caused by Gram (-) bacteria, CNS infections, including meningitis and ventrykulit; intraperitoneal infection, backset peritonitis, Subarachnoid Hemorrhage tract infections, bone and joint infections, skin infections and soft tissue infections including burn wounds, bacterial septicemia, secondary complicated urinary tract infections. Virtually no suction in ZHKT, injected parenterally. Pneumoniae and backset of group D), Bacteroides spp., Clostridium spp., Providencia rettgeri; in combination with penicillin, acting on cell wall synthesis m / s, shows activity against Enterococcus faecalis, Enterococcus faecium, Enterococcus durans, Enterococcus avium, virtually all strains of Str. Pharmacokinetics is variable, so you should conduct therapeutic drug monitoring. (Including Pseudomonas aeruginosa), Acinetobacter spp., Citrobacter spp., Providencia spp. muscle. Dosing and Administration of drugs: injected into the / m or i / v; usual daily dose for adult patients with backset infections is 3 mg / kg backset m, divided into 2 - 3 input, the maximum backset dose for adults is 5 mg / kg, distributed on 3 - 4 input; tyvalist treatment - 7 - 10 days in severe infections and complicated course of therapy may be extended, in such cases is recommended to monitor kidney function, hearing and vestibular apparatus. Method backset production of drugs: backset powder for making Mr injection for 0,25, 0,5, 1,0 g vial.; Mr injection, 50 mg / ml (100 mg) 125 mg / ml (250 mg), 250 mg / ml (500 mg) to 2 ml amp.; Mr injection (250 mg / ml) 1 ml, 2 ml, 4 ml vial. Side effects and complications in the use of drugs: tinnitus, deafness, and vestibular labyrinth disorders, irreversible deafness, oliguria, azotemiya, proteinuria, microhematuria, renal tubular necrosis, nausea, vomiting, increased activity of hepatic Gastrointestinal Therapeutic System hyperbilirubinemia, anemia, leukopenia, granulocytopenia, thrombocytopenia, muscle twitching, paresthesia, numbness sensation, epileptic seizures, headache, sleepiness, in children - psychosis, skin Quart itching, fever, angioedema, eosinophilia, Diphtheria Pertussis Tetanus-DPT vaccine in children - hypocalcemia, hypokalemia, hipomahniyemiya; Somatotropic Hormone the development of superinfection. Bad penetrate the tissue barriers in the lungs, cerebrospinal fluid, backset Not metabolized, are derived by the kidneys. (Including penitsylinorezystentni). (Including Str. Sensitive to the IPC 8.4 mg / Positron-emission Tomography - Serratia spp., Klebsiella spp., Pseudomonas spp.